Endocrine Abstracts

Unilateral forms of primary aldosteronism (PA) should, by inference, have a contralaterally normal and therefore suppressed adrenal zona glomerulosa. However, there is no agreed definition of expected adrenal suppression. We hypothesized two biochemical definitions of adrenal suppression based upon measurements done during adrenal vein sampling. These were then applied to a PA–AVS-outcomes database to determine whether either definition proved useful for interpretation of...

Introduction: Adrenal vein sampling (AVS) is considered gold-standard for diagnosis of unilateral primary aldosteronism (PA), and necessary pre-surgery. Imaging-AVS discordance may occur in up to 30-40% of PA-AVS series, and presents a diagnostic dilemma which may preclude surgery. Lateralization by AVS is defined as the ratio of aldosterone concentrations normalized by cortisol from each adrenal vein, and is thus sensitive to any pathologic asymmetry in corti...

Objective: The 2016 ATA RR assessment recommendations for patients with DTC were based on retrospective studies. We present the first outcomes of a prospective assessment of thyroid cancer management according to the ATA RR stratification.Methods: Using the Calgary prospective thyroid cancer database, we identified 612 patients with differentiated thyroid cancer (DTC) treated at our centre between April 2017 and December 2021. Each case was reviewed by t...